ATP Cofactors™ is a specially formulated high potency vitamins B-2/B-3 combination, containing 100 mg of Riboflavin and 500 mg of Niacin (as inositol hexanicotinate) per tablet. ATP Cofactors™ is intended to be used as part of a complete nutritional program, emphasizing magnesium instead of calcium.
SUGGESTED USE: One to three tablets daily, or as recommended by a healthcare provider. When used in conjunction with Iodoral® 50 mg tablets, the recommended amount is one tablet of ATP Cofactor for each 50 mg tablet of Iodoral®.
Rationale for the use of ATP Cofactors™ As previously discussed, ATP is the universal currency of energy used in biological systems to maintain an organism in a state that is far from thermodynamic equilibrium with the environment, that is far from death. The active from of ATP is a complex of ATP with mainly magnesium, but also with manganese. In case of manganese deficiency, magnesium can replace manganese. The turnover of ATP is extremely high. For example, a human at rest consumes one half of his/her weight of ATP daily. The synthesis of ATP from ADP plus high energy phosphate group is called oxidative phosphorylation and is dependant on the electron flow through the electron transport chain via electron carriers. NADH and FADH2 are the major electron carriers in the synthesis of ATP. The B vitamins, niacin and riboflavin, are the precursors of the Cofactors NADH and FADH2. These Cofactors play an important role also in the oxidation and organification of iodide by generating hydrogen peroxide via the NADPH oxydase system. In some conditions, the body cannot efficiently synthesized NADH and FADH3 from Niacin and Riboflavin because of defect/damage to the enzymes involved in this conversion. More Riboflavin and Niacin are needed to override the inefficient enzymes in order to obtain adequate levels of cofactors. There is evidence that a lack of these vitamins can lead to a deficient organification of iodide. Preliminary results suggest that high dosage of vitamins B-2 and B-3 combined with 100-150 mg of elemental iodine in the form of Lugol tablets can help support overall well being.
WARNING: The urine may turn dark yellow due to the excretion of riboflavin and may stain undergarment in subjects with urinary incontinence. The flushing associated with niacin does not occur because the formula uses a non flushing form of niacin.